For example, GLP-1R in adipocytes can directly regulate apoptosis and preadipocyte proliferation by activating the adenylate cyclase/cyclic adenosine monophosphate (AC/cAMP) signaling pathway and various cell signaling cascades, including extracellular signal-regulated kinase (ERK), protein kinase C (PKC), and protein kinase B (AKT) [41,46]
In 2006, Bruno et al
It plays a key role in turning the food we eat into energy, repairing damaged DNA, and activating sirtuins, a group of enzymes that help regulate metabolism, stress response, and aspects of healthy aging
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