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Brain behavior immunity-health (2021) 17:100335

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Pregnancy Safety Registries: Ongoing pharmacovigilance and pregnancy exposure registries are necessary to define teratogenic risk and optimal discontinuation intervals

The half-life is short, roughly 10 to 12 minutes

In individuals homozygous for the C677T polymorphism in the MTHFR gene, low riboflavin status is associated with elevated plasma homocysteine, and in turn linked with a higher risk of cardiovascular disease and other chronic diseases (13, 14)