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Evans AM et al

Its defining structural feature is the gamma-glutamyl linkage: the glutamate residue is joined through its side-chain carboxyl rather than the usual alpha-peptide bond, which makes the molecule resistant to most intracellular peptidases and means it is cleaved almost exclusively by gamma-glutamyl transpeptidase at the outer cell surface (Zhang, Forman and Choi, Methods in Enzymology, 2005)

Curcuma for Autoimmune Modulation: Multiple sclerosis, RA, type 1 diabetes, inflammatory bowel disease, myocarditis, thyroiditis, uveitis, systemic lupus erythematosus, and myasthenia gravis are organ-specific autoimmune diseases that afflict more than 5% of the population worldwide

Quick treatment ensures infections are resolved before they become serious

Missing doses undermines the cumulative signaling effect