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Step 4: Prepare your dose of Ozempic Dial the dose counter so the desired dose lines up with the dose pointer

The native human GLP-1 peptide is biologically powerful but pharmacologically useless on its own: it has a circulating half-life of around 90 seconds, because the dipeptidyl peptidase-4 (DPP-4) enzyme cleaves it almost as fast as it is released and the kidneys clear what remains

4 in Supplementary Table 3, for Fig.5 in Supplementary Table 4, for Fig

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The following chart represents the most commonly referenced dose equivalencies used in clinical practice