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Spearman correlation analysis was used in patient sample experiments
Stability in any given laboratory still depends on temperature, pH, light exposure, and freeze-thaw history all of which should be documented per lot
At The Face Clinic, safety protocols include: Conservative laser settings for Fitzpatrick IVV skin Patch testing when clinically indicated Avoidance of excessive heat triggers in active melasma Gradual protocol progression rather than one-session promises Structured post-care to protect healing skin and prevent rebound pigmentation When We May Delay or Modify Treatment Certain situations require caution or adjustment: Pregnancy or breastfeeding (some modalities are postponed) Active eczema, infection or skin irritation Recent use of strong retinoids or aggressive peels History of severe PIH or very reactive skin This cautious approach aligns with guidance shared by professional dermatology bodies such as the British Association of Dermatologists for pigmentation-prone skin
Hewlings, S
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