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Therefore, during brain disorders such as AD, the BBB damage due to disruption of TJ integrity compromises the chemical composition of the neuronal milieu, leading to dysfunction of neuronal circuits with progressive synaptic loss and neuronal death (Zlokovic, 2008)
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Those speaking for the company believe there is reason to be optimistic that the clinical trial will show a synergistic benefit, in which the most significantly positive results will be seen in patients supplementing with a combination of the two ingredients
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