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The pivotal SURMOUNT trials did not identify mood disorders or emotional disturbances as significant safety signals, and depression and anxiety were not reported at notably higher rates compared to placebo groups
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Additionally, participants saw an increase in C-peptide, which shows that their bodies were making more insulin after being on the therapy
For example, if a particular drug can withstand extended amounts of heat stress then a smaller concentration of APTES such as 0.1% should be utilized
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