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In addition, we have observed increased neuronal activation in the LH upon OB GLP-1R stimulation and the existence of an anatomical connection between the AON and LH
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GLP-1 drugs can have significant side effects, especially gastrointestinal issues related to constipation or nausea
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These SAR studies have contributed foundational understanding of the conformational determinants of melanocortin receptor subtype selectivity
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