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[6] Because systemic absorption of topically applied GHK-Cu seems minimal, clinically significant pharmacokinetic interactions with oral medications are unlikely

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Interactions between c-MET II and HGF I Distinct to the binding mode between c-MET I and HGF I that involves multiple domains of HGF, only the K1 domain located on the opposite side of HGF I makes direct contact with c-MET II, indicating that HGF-K1 is essential for c-MET activation (Fig