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The connection between GLP-1 and vision loss extends beyond NAION to include several other eye-related issues: Optic neuropathy : Damage to the optic nerve affecting signal transmission from the eye to the brain Retinal ischemia : Inadequate blood supply to the retina causing tissue damage Diabetic retinopathy exacerbation : Acceleration of existing retinal blood vessel damage in diabetic patients Extensive Research: Indicates that patients using semaglutide-based medications face elevated risks of developing these GLP-1 eye problems