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Drug discovery trials, including those funded by NIH, would benefit from including measures for mechanistic hypothesis in addition to primary clinical endpoints in early-stage trials to accelerate future therapeutics development regardless of trial success
Ipamorelin is a synthetic pentapeptide and a selective agonist of the ghrelin / growth-hormone-secretagogue receptor (GHS-R1a)
Alternative clinical pathway
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Researchers frequently investigate GHRP-6 because it may influence hunger-related pathways through ghrelin receptor activity
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