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These drugs all show marked improvement in metabolic conditions including DM, NASH, hypertension, and unfavorable lipids with impact dependent on the degree and persistence of weight loss (the key to reduced mortality)

This group tends to appreciate the program's non-disruptive format and the absence of stimulants, recognizing that their metabolism and hormone profiles are no longer compatible with rapid or aggressive interventions

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AD is characterized by a decade-long prodromal stage, and dementia diagnosis typically occurs in the late biological stage of AD, by which time substantial amounts of A and tau proteins have accumulated in the cortex [101]