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Dementia 1991;2(6):333-337
The critical pharmacological balance is that the GLP-1R activation offsets the hyperglycemic tendency of glucagon receptor agonism
GLP-1 agonists bind to GLP-1 receptors on pancreatic beta cells, stimulating glucose-dependent insulin secretionmeaning insulin is released only when blood glucose levels are elevated
Monitor for signs of inadequate disease control, such as elevated blood glucose readings, increased thirst, frequent urination, or unexplained weight changes
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