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(If YES, contraindicated)- Does the patient have a history of melanoma or abnormal skin pigmentation

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a 2025 IV pilot in two adults used 10 mg and 20 mg single infusions and reported no adverse effects (Lee et al., Alternative Therapies in Health and Medicine)

Nevertheless, the expression of these NKG2D ligands open the way to use CAR-T cell therapy based on the recognition of these molecules overexpressed on the cell surface of senescent cells