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A small percentage report decreased appetite, which is actually the desired effect, not a side effect

Available at: [accessed March 2026]. Reducing BMI below the obesity threshold in adolescents treated with once-weekly subcutaneous semaglutide 2.4 mg (STEP TEENS post hoc analysis)

When appetite decreases, nutrition has to work harder

Understanding Zepbound's peptide structure helps explain its administration route, storage requirements, and clinical effects on weight management