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Despite the evidence converging toward one obvious conclusion, I have to be honest and tell you that no well-controlled randomized human clinical trials exist evaluating BPC-157 efficacy for any indication
However, that study had few GLP-1 receptor agonist users (n=501), leading to an inability to assess self-harm separately and imprecise estimates.8 In a more recent study, semaglutide was found to be strongly associated with a decreased risk of both incident and recurrent suicidal ideation separately among patients with type 2 diabetes and with overweight or obesity (hazard ratios 0.27 (95% CI 0.20 to 0.36) for incident suicidal ideation and 0.44 (0.32 to 0.60)for recurrent suicidal ideation among patients with overweight or obesity
Any observed clinical changes in trials are specific to those study designs and should not be generalized as established therapeutic effects outside a regulated research context
Both reduce food intake, but through different mechanisms
While no single hormone determines body weight, supporting your body's natural GLP-1 response may make it easier to maintain healthy eating patterns over time
