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A network meta-analysis published recently confirmed this pattern, finding that retatrutide demonstrated greater absolute weight reduction compared to tirzepatide (retatrutide: MD -16.34 kg vs tirzepatide: MD -11.82 kg)
Food Chemistry, 2004, 86 (1), 137142
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However, its important to note that using Semaglutide GLP-1 for weight loss in individuals with a BMI below 27 is not currently supported by clinical data or FDA approval
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