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Metabolism MOTS-c activates AMPK, the metabolic switch

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Glutathione precursors replenish decreased glutathione pool in cystinotic cell lines

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Pooled results from seven non-pharmacological trials were associated with a statistically significant 48% relative reduction of TIN risk with low heterogeneity and the pooled results from six pharmacological trials were associated with a significant 20% relative reduction of TIN risk with moderate heterogeneity