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A randomized, double-blind, placebo-controlled trial in 191 older adults (75 years) with moderate vitamin B 12 deficiency (serum cobalamin concentrations of 107-210 pmol/L) without anemia provided participants with 1 mg/day of cyanocobalamin for one year (94)
& Meier-Ewert, K
Most patients report a noticeable energy lift within 24 to 72 hours of a B12 shot, with peak effects around day 1 to 3 post-injection
Subcutaneous (into the fat just under the skin)
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