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Perhaps its most famous role, GLP-1 crosses the blood-brain barrier to act directly on appetite centres in the brain, enhancing feelings of fullness and reducing hunger signals
Vagus nerve as modulator of the braingut axis in psychiatric and inflammatory disorders
Trautmann ME, Van Gaal L, Han J, Hardy E
Most side effects are manageable and may decrease with time, while others may require more attention
Conclusion : Semaglutide, originally developed for the treatment of type 2 diabetes and obesity, offers a significant breakthrough in reducing the risk of cardiovascular disease
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