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GLP-1 Use by Indication This means that gender differences appear strongest in weight-loss-driven use, not diabetes care

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Several major randomized controlled trials (RCTs) have confirmed the efficacy and safety of GLP-1RAs in adults with diabetes 17 and obesity 18 , and more recently in child and adolescent populations living with obesity 19,20

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Tirzepatide's clinical durability (sustained efficacy beyond 12 weeks, unlike phentermine) aligns with long-term weight management goals rather than short-term appetite suppression

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