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Additionally, individuals with a history of pancreatitis or severe gastrointestinal disease should avoid these medications
However, it is not without risks, and its legality can be an issue in certain countries
A 2023 preclinical study published in Nature Metabolism demonstrated that GLP-1 receptor activation suppressed reward-seeking behavior in animal models exposed to both food and alcohol cues
Meanwhile, a study published in JAMA found that people taking tirzepatide drugs (e.g., Zepbound) have double the chance of developing NAION, a type of blindness
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