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Description

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In the drugs best showing so far, the ATTAIN-1 trial, people taking orforglipron lost on average 12.4% of their baseline weight, a notch below the roughly 14% weight loss seen in similar trials of Novo Nordisks injectable Wegovy and also below the typical results seen with Eli Lillys tirzepatide, a dual GLP-1/GIP medication

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46, W296-W303

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Harada, Effects of metformin on blood glucose levels and bodyweight mediated through intestinal effects

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This makes access harder for people who need them only for weight loss

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