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Epitalon has been shown to significantly increase the expression of key antioxidant enzymes: Superoxide dismutase (SOD-1) Catalase NAD(P)H quinone dehydrogenase 1 (NQO1) These effects are mediated via the Keap1/Nrf2 signaling pathway [40, 41]: a master regulator of cellular redox balance
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For those on compounded formulations, dosing flexibility may be greater
Such an effect could aggravate indirectly the detrimental action of oxidative stress on neurons, which is particularly enhanced in the progression of neurodegenerative diseases
it also serves many other purposes
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