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The authors acknowledge several limitations

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Nonclinical Toxicology 13.1 Carcinogenesis, Mutagenesis, Impairment of Fertility JANUMET No animal studies have been conducted with the combined products in JANUMET to evaluate carcinogenesis, mutagenesis or impairment of fertility

Bei der Anwendung mit anderen Medikamenten knnen Wechselwirkungen auftreten: Bei Kombination mit Medikamenten zur Blutgerinnung muss diese mit regelmigen Blutuntersuchungen strker beobachtet werden