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therefore, we can assume that our observations were the result of local GLP-1R stimulation and not the result of feed-forward circuit-level changes

Potential Eye Health Risks While GLP-1 agonists have been heralded as life-changing for some individuals, recent studies and case reports suggest a connection between these drugs and certain eye health complications, particularly diabetic retinopathy and other forms of vision impairment

This can be done with any dose

In a research letter published in JAMA Network Open in August, the authors purchased off-brand forms of semaglutide from six online pharmacies

Clinical trials show that nausea affects approximately 44% of patients taking semaglutide (Wegovy) and about 24-40% of those on tirzepatide (Zepbound), with rates varying by dose