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Han C, Xiong N, Guo X, Huang J, Ma K, Liu L, et al

GHK-Cu has been studied for its role in collagen and glycosaminoglycan activity, both of which are connected to skin structure and repair

Body-Composition Research The GH/IGF-1 axis is closely related to body composition, including lean tissue signaling, lipid metabolism, tissue remodeling, and age-related changes in the somatotropic axis. Research on GHRH analogs, including sermorelin-related compounds, has explored effects on GH pulses, IGF-1, and lean-to-fat ratio in older adults. These findings do not directly prove body-composition benefits for all forms of CJC-1295, but they support the broader rationale for studying GHRH analogs in this area

Data were pooled using random-effects models with subgroup analyses by drug type and treatment duration (3, 6, and 12 months)