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The variability is significant

It is quickly degraded by DPP-4, limiting its physiological duration of action

To determine whether these effects depend on RAMP-containing amylin receptor subtypes (AMY1R and AMY3R), experiments were conducted in HFD-fed WT and RAMP1/3 double knockout (KO) mice

The study assessed weight loss in two groups of Virta members with type 2 diabetes: those for whom (a) GLP-1s were fully deprescribed and (b) GLP-1s were continued

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