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The Bd isolates (#46 Waste point- Litoria verreauxii #5-2013-LB, RW, #109 Melbourne-Lissotriton vulgaris-2023-LB, and #87 NarielValley-Litoria.spenceri-2020-LB) were isolated from naturally infected amphibians in Australia, and all belong to the virulent Global Pandemic Lineage (GPL)
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The co-expression of ST and RAS V12 leads to the upregulation of topoisomerase I, thereby increasing cellular susceptibility to Erastin (Dolma et al., 2003)
On the other hand, there is now unanimous consensus for stages III and IV that only ART is effective (6)
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