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The broken-down fat is then naturally metabolised and eliminated by the body's lymphatic system

While endogenous biosynthesis of l-carnitine from the amino acids lysine and methionine is sufficient for essential processes along with dietary sources of carnitine from protein-rich red meat, for example dietary supplementation of carnitine may pose benefits in certain physiological conditions

This data comes from animal models and may not translate directly to human physiology

Exploring potential synergistic effects of GLP-1RAs with other established therapies, such as SGLT2 inhibitors, could unlock combination approaches for improved outcomes