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Moreover, SM-PNPs ameliorated HFD-induced alterations in fasting glucose and insulin levels and improved HOMA-IR indices, thereby restoring glucose homeostasis

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The TgAPParc mouse model, which carries the E693G mutation (APP695) under the control of the murine Thy1.2 promoter, exhibited 3- to 7-fold higher mutant human APP expression compared to endogenous mouse APP

Result: The diarrhea rate in the experimental group decreased by 18%, daily weight gain increased by 22%, and survival rate increased by 5%

10.1016/j.psyneuen.2012.05.008 41 DixitS.WhooleyM