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For example, p38-MAPK, the end of Jun N-terminal kinase (JNK), and cell-cycle dependent kinase affect the plasticity of gene transcription (Ittner et al., 2010)

Typically dormant under normal conditions, HSCs become active during liver damage, transforming into myofibroblasts that contribute to liver fibrosis

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Additionally, reduced water consumption decreases saliva production, which normally protects throat tissue from irritation