The nuclear glutathione pool is more resistant to depletion by BSO than the cytosolic as it was demonstrated in 3T3 fibroblasts and other human cell lines 87,88 , hence we cannot exclude the possibility that AITC -which presumably acts differently from BSO- is able to deplete efficiently the nuclear pool
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PubMed Bock-Marquette, I., Saxena, A., White, M.D., Dimaio, J.M., & Srivastava, D
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