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This medication is not recommended for people with a personal or family history of medullary thyroid carcinoma or multiple endocrine neoplasia syndrome type 2
Dosing strategies are individualized and typically begin at lower levels to allow the body to adjust
At a molecular level, nothing fundamental has changed
It should be used with caution in patients with a history of pancreatitis and is not recommended for use in pregnant or breastfeeding individuals
Obesity and Weight Studies: Published Phase 2 data (NEJM, 2023) showed up to 24.2% mean body weight reduction at 48 weeks
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