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Early to moderate type 2 diabetes For patients with type 2 diabetes who have not achieved adequate control with metformin alone, GLP-1 receptor agonists are increasingly the second-line choice

doi: 10.1152/ajpendo.00499.2003 17 NauckMAMeierJJ

Since there is increased OCTN2 expression in the small intestine in response to oxidized fat, and OCTN2 binds not only carnitine but various drugs, it is suggested by the authors that OCTN2 might be harnessed to improve absorption of various drugs [112]

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This finding is particularly important given the obesity population's inherent cardiovascular risk