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Direct SlC7A11 overexpression in cardiac myocytes boosted GSH levels and reduced cardiac ferroptosis and injury, suggesting that it is feasible to fortify GSH levels by increasing SLC7A11 [76]

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Often called the "master antioxidant," glutathione is touted for its pivotal role in protecting cells from oxidative stress, which helps support the body's detoxification process, immune system and liver function

Plotting the fluorescence intensity ratios with excitation wavelengths at 405 and 488 nm (F 405 /F 488 ) as a function of GSH concentrations confers a superb linear relationship ( R 2 =0.998) covering the physiological GSH concentration range 110 mM (Fig