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1 Adrenal Fatigue and Weight Loss While the relationship between adrenal fatigue and weight gain is straightforward adrenal fatigue is associated with higher cortisol levels, which increases appetite and overeating, eventually leading to weight gain the relationship between Adrenal Fatigue and weight loss is not as clear cut

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Typical Weekly Pattern During This Phase Weight loss: 1-2 pounds weekly early in phase, gradually decreasing to 1-1.5 pounds weekly by week 24 Appetite: Strongly suppressed throughout

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