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If metabolism and reward are tightly linked, the rationale for potential use in cannabis use disorder is that a stronger metabolic signal might produce a stronger behavioral effect

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Nausea, vomiting, diarrhea, and constipation appear in clinical trials at rates between 15% and 40%, depending on dose and individual factors

Their larger, more intricate structures don't typically interact with standard immunoassay antibodies, nor do they often produce predictable fragmentation patterns conducive to routine GC-MS analysis without extensive, specialized preparation