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10.1172/JCI112855 91 MorettoT
doi: 10.1038/s41467-024-47273-w 246 LaiYXiongP
The incidence of cramping in clinical trials variessome patients report mild, infrequent episodes while others experience discomfort that interferes with exercise or sleep
It may be more fun to ask the questions than to know the answer
Once a drug products range of allowable denaturation has been identified, the next step in this process requires full denaturation of the protein solution as confirmed via physical separations of aggregates or characterization of tertiary or secondary structural changes
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