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Two Previous studies [1, 25] addressing NAC use were limited to only modest doses of NAC (6001200 mg/day) and short duration of treatment (8 weeks) and showed a 32% significant improvement in glutathione peroxidase levels and a 6% improvement in pain score, with a recommendation of the use of higher doses of NAC for longer duration

Variations in these genes can impair this protective function, leading to increased oxidative stress

Affinity chromatography of hepatic glutathione S-transferases on omega-aminoalkyl sepharose derivatives of glutathione

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