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Diabetes Metab Syndr Obes 16:24332446 Volpe S, Lisco G, Fanelli M, Racaniello D, Colaianni V, Lavarra V et al (2023) Oral semaglutide improves body composition and preserves lean mass in patients with type 2 diabetes: a 26-week prospective real-life study

In a 2025 double-blind pilot (48 adults with AUD), once-weekly low-dose semaglutide cut craving scores and reduced total drinks by roughly 40 percent after eight weeks

Think of it as an exercise-mimetic signal amplifier

Some patients come in specifically asking about peptides, while others are introduced to them as part of a broader wellness or longevity plan