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Confirm theres genuine medical supervision

These populations face compounded cardiovascular risk from multiple metabolic derangements, and semaglutide addresses multiple pathways simultaneously, offering comprehensive protection rather than single-target therapy

40 In the FIGHT trial, long-term administration of liraglutide to HF and HFrEF patients with or without diabetes did not significantly improve LVEF after 24 weeks of treatment

Furthermore, the trim and fill model did not identify any missing studies, corroborating the robustness of the findings

It says these warrant investigation to rule out confounding conditions rather than being assumed to be medication effects