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The Journal of Biological Chemistry 277(6): 4223-4231
Int J Epidemiol 2017;46:799-800.PubMed 17
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Its substitutions at amino acid positions 2, 8, 15, and 27 improve resistance to enzymatic degradation, extending half-life to approximately 30 minutes while maintaining natural GH pulsatility.Ipamorelin, a selective GHS, binds to the ghrelin receptor (GHS-R1a) to further enhance GH release
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