This compound is supplied strictly for laboratory research purposes and is not approved for human or veterinary use
What are B12 Shots
There are many agents with a well known depigmenting effect like pycnogenol, orchid extract, marine algae extract, cinnamic acid, soy, aloesin, Boswellia , hydroquinone, glycolic acid, arbutin, kojic acid, ascorbate, tocopherol, niacinamide, etc
Lupia RH, Ferencz N, Lertora JJ, Aggarwal SK, George WJ, Agrawal KC
Tri-Luma cream containing hydroquinone 4%, tretinoin 0.05%, and fluocinolone acetonide 0.1% has been authorized by the FDA for melasma management and should be applied once daily on the affected facial areas for at least 8 weeks (Ferreira Cestari et al., 2007