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Contraindications Do Not Use If You Have a known hypersensitivity to cobalt or any ingredient in the formulation (rare) Have Lebers disease (hereditary optic nerve atrophy) cyanocobalamin can cause rapid optic nerve atrophy Warnings and Precautions Hypokalemia (low potassium): May occur during initial treatment of severe megaloblastic anemia

Similarly, when increasing the minimum thresholds for average daily dose received in the analysis of MOF, differences between the two groups became larger and increasingly significant

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