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These receptors can be found throughout the brain, thyroid, adrenal glands, fat tissue, pancreas, and muscular heart tissue
doi: 10.1002/cmdc.202200583 240 LincoffAMTardifJCSchwartzGGNichollsSJRydnLNealBet al
Estrogen withdrawal is implicated in lower blood serotonin combined with up-regulation (increased gene expression) of specific serotonin receptors attached to brain cells
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