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The phase 2 and phase 3 trials focused primarily on total body weight reduction
However, cancer cells often adapt to oxidative stress by upregulating CHAC1, which can help them manage and exploit oxidative environments, leading to increased resilience and survival
doi: 10.1111/ppa.12893 49 Mndez-LpezE.DonaireL.GoslvezB.Daz-VivancosP.Snchez-PinaM
Mammalian esophageal stratified tissue homeostasis is maintained distinctively by the epithelial pluripotent p63+Sox2+ and p63Sox2+ cell populations
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Holowatz and Kenney, 2011
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