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Biomarkers One kidney perfused as part of the trial was discarded based on an abnormally elevated vascular resistance

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Trp53 fl/fl ) or intracolonic induction of colon tumours by submucosal injection of 100 M 4-hydroxytamoxifen (Sigma-Aldrich) in 810-week-old AKP mice (Villin-CreER T2

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