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nevertheless, additional studies would be suited to further corroborate the encouraging results presented by the current study, and to further widen the field of l-ARG supplementation clinical applicability

On the basis of novel data and hypothesis on the possible role of scarce glutathione (GSH) levels in the exacerbation of COVID-19 and of the GSH depleting activity of PAC, this commentary raises the question of whether PAC may be the better choice