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The analgesic efficacy of donepezil was also demonstrated in several other CIPN rat models (bortezomib, paclitaxel, and vincristine) and did not alter the viability of cancer cells or the efficacy of anticancer drugs [165]

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Similarly, drugs like cyclosporine that target mPTP are not entirely specific to injured cells they might prevent desired apoptosis of severely damaged cells, potentially leading to necrosis instead

Sermorelin may help restore the natural growth hormone pulses that decline with age